Whole blood transcriptome comparison of pigs with extreme production of in vivo dsRNA-induced serum IFN-a.
Liu X1, Huang J2, Yang S3, Zhao Y3, Xiang A3, Cao J3, Fan B3, Wu Z4, Zhao J5, Zhao S3, Zhu M6. Dev Comp Immunol. 2013 Dec 1;44(1):35-43.
Liu et al designed a transcriptomic analysis to describe the whole blood differential transcriptional response to dsRNA by pigs with high vs. low IFN alpha levels. PathVisio was used to visualize the regulatory mechanism of the induction of interferon in pig cells.